Description

2-Trifluoromethyl-3-Cyanopyridine is a high-value, multi-functional heterocyclic building block characterized by its trifluoromethyl and cyano substituents. This compound is essential for introducing lipophilicity and metabolic stability into target molecules, making it a critical intermediate in advanced chemical synthesis. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors and central nervous system (CNS) targeted drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Liquid Crystal & OLED Materials: Employed in the synthesis of electron-deficient components for electronic and optoelectronic applications.
• Chemical Biology & Proteomics: Utilized as a versatile scaffold for designing molecular probes and enzyme inhibitors in biochemical research.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions like Suzuki-Miyaura and Buchwald-Hartwig aminations for complex molecule assembly.

Basic Information

Product Name	2-Trifluoromethyl-3-Cyanopyridine
CAS No.	870066-15-2
Molecular Formula	C7H3F3N2
Molecular Weight	172.11 g/mol
Synonyms	3-Cyano-2-(trifluoromethyl)pyridine; 2-(Trifluoromethyl)nicotinonitrile; 2-(Trifluoromethyl)-3-pyridinecarbonitrile; 3-Pyridinecarbonitrile, 2-(trifluoromethyl)-; 2-Trifluoromethylpyridine-3-carbonitrile
EINECS	Contact for details

Quality Control

Our 2-Trifluoromethyl-3-Cyanopyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee compliance with your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if necessary to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.