Description

Benzofuran-5-Ylmethanesulfonyl Chloride CAS NO 869885-60-9 is a specialized sulfonyl chloride derivative of the benzofuran scaffold, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as an electrophile, enabling the efficient introduction of the sulfonamide or sulfonate moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and material science industries who are developing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of potential drug candidates, particularly for creating sulfonamide-based pharmacophores with diverse biological activities.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that incorporate the benzofuran structure for enhanced efficacy.
• Material Science: Acts as a precursor for functional polymers and advanced organic materials requiring specific sulfonyl group integration.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling, cross-linking, or modifying biomolecules in probe development.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up processes under GMP or non-GMP conditions.
• Academic & R&D Laboratories: Fundamental research tool for exploring new synthetic methodologies and reaction pathways involving heterocyclic sulfonyl chlorides.

Basic Information

Product Name	Benzofuran-5-Ylmethanesulfonyl Chloride
CAS No.	869885-60-9
Molecular Formula	C10H7ClO3S
Molecular Weight	242.68 g/mol
Synonyms	5-(Chlorosulfonylmethyl)benzofuran; 1-(Benzofuran-5-yl)methanesulfonyl chloride; Benzofuran-5-ylmethanesulfonyl chloride; (Benzofuran-5-ylmethyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our Benzofuran-5-Ylmethanesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is analyzed using advanced techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.