Description

2,6-Difluoro-3-Cyanopyridine is a high-value, multi-functional pyridine derivative characterized by its fluorine and nitrile substituents. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern synthetic chemistry. It is primarily utilized by R&D chemists and process development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and catalysts used in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Fluorinated Compound Library: A valuable reagent for medicinal chemistry teams building diverse compound libraries to explore structure-activity relationships (SAR).

Basic Information

Product Name	2,6-Difluoro-3-Cyanopyridine
CAS No.	869557-17-5
Molecular Formula	C6H2F2N2
Molecular Weight	140.10 g/mol
Synonyms	3-Cyano-2,6-difluoropyridine; 2,6-Difluoronicotinonitrile; 2,6-Difluoropyridine-3-carbonitrile; Pyridine-3-carbonitrile, 2,6-difluoro-; 869557-17-5; 2,6-Difluoro-3-pyridinecarbonitrile
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Cyanopyridine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency. We provide detailed Certificates of Analysis (COA) with each shipment, documenting identity, purity, and impurity profiles to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the original container tightly sealed and consider storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.