Description

3-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester is a high-purity fluorinated pyridine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and the ester group, which enables precise molecular modifications for developing novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for creating active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), especially in fluorinated drug candidates targeting CNS disorders and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of fluorinated organic semiconductors, liquid crystals, and other functional materials.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags used in bioimaging and diagnostic assays.
• Custom Synthesis and Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	3-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester
CAS No.	869108-35-0
Molecular Formula	C7H6FNO2
Molecular Weight	155.13 g/mol
Synonyms	Methyl 3-fluoropyridine-2-carboxylate; 3-Fluoro-2-pyridinecarboxylic acid methyl ester; 2-Pyridinecarboxylic acid, 3-fluoro-, methyl ester; 3-Fluoropicolinic acid methyl ester; Methyl 3-fluoropicolinate; 3-Fluoro-2-(methoxycarbonyl)pyridine
EINECS	Contact for details

Quality Control

Our 3-Fluoro-Pyridine-2-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, confirming compliance with agreed specifications. Our quality commitment supports applications in GMP and ISO-regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.