Description

1-Acetyl-1,2,3,4-Tetrahydro-Quinoline-6-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the efficient introduction of the sulfonamide functional group, a key moiety in the development of bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel drug candidates and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those targeting neurological and metabolic disorders.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the sulfonamide group for biological activity.
• Material Science Research: Employed in the creation of novel polymers and functional materials with specific sulfonated properties.
• Chemical Biology Probes: Acts as a versatile reagent for labeling and modifying proteins or other biomolecules in research settings.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of complex, sulfonamide-containing target molecules for clients.

Basic Information

Product Name	1-Acetyl-1,2,3,4-Tetrahydro-Quinoline-6-Sulfonyl Chloride
CAS No.	868964-04-9
Molecular Formula	C₁₁H₁₂ClNO₃S
Molecular Weight	273.73 g/mol
Synonyms	6-(Chlorosulfonyl)-1-acetyl-1,2,3,4-tetrahydroquinoline; 1-Acetyl-6-(chlorosulfonyl)-1,2,3,4-tetrahydroquinoline; ATQ-SO2Cl; 1,2,3,4-Tetrahydro-1-acetyl-6-quinolinesulfonyl chloride; Quinoline-6-sulfonyl chloride, 1-acetyl-1,2,3,4-tetrahydro-; 868964-04-9
EINECS	Contact for details

Quality Control

Our 1-Acetyl-1,2,3,4-Tetrahydro-Quinoline-6-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.