Description

2-Amino-5-Bromopyridine-3-Sulfonyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its unique structure, featuring both a reactive sulfonyl chloride group and a halogenated aminopyridine core, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and antimicrobial agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides that require a halogenated pyridine scaffold.
• Material Science Research: Serves as a precursor for creating functionalized polymers and metal-organic frameworks (MOFs) with specific electronic properties.
• Chemical Biology Probes: Employed in the development of activity-based probes and covalent inhibitors for target identification and validation studies.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized heterocyclic dyes and colorants.

Basic Information

Product Name	2-Amino-5-Bromopyridine-3-Sulfonyl Chloride
CAS No.	868963-98-8
Molecular Formula	C5H4BrClN2O2S
Molecular Weight	271.52 g/mol
Synonyms	5-Bromo-2-aminopyridine-3-sulfonyl chloride; 3-Pyridinesulfonyl chloride, 2-amino-5-bromo-; 2-Amino-5-bromo-3-pyridinesulfonyl chloride; 5-Bromo-2-pyridinamine-3-sulfonyl chloride; 868963-98-8; ABPS-Cl
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Bromopyridine-3-Sulfonyl Chloride is manufactured under strict quality management systems and undergoes comprehensive analytical testing. We ensure compliance with stringent internal specifications, which are aligned with industry best practices for advanced pharmaceutical intermediates. A detailed Certificate of Analysis (COA) providing purity, identity, and impurity profile is supplied with each shipment to guarantee traceability and consistency for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.