Description

3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Sulfonyl Chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. Its value lies in enabling the precise introduction of the sulfonamide pharmacophore, a key structural motif in modern medicinal chemistry. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of small molecule drugs, particularly those targeting kinase inhibition and other enzyme-related pathways.
• Agrochemical Synthesis: Used in the development of novel herbicides and fungicides, where the sulfonamide group contributes to biological activity.
• Chemical Biology Probe Development: Employed in the creation of activity-based probes and other research tools for studying protein function and interaction.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialized polymers with unique properties.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing complex molecules for clients.

Basic Information

Product Name	3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Sulfonyl Chloride
CAS No.	868962-24-7
Molecular Formula	C8H6ClNO4S
Molecular Weight	247.66 g/mol
Synonyms	7-(Chlorosulfonyl)-2H-1,4-benzoxazin-3(4H)-one; 3-Oxo-3,4-dihydro-2H-1,4-benzoxazine-7-sulfonyl chloride; 2H-1,4-Benzoxazin-3(4H)-one, 7-(chlorosulfonyl)-; 7-Chlorosulfonyl-3,4-dihydro-2H-1,4-benzoxazin-3-one; 868962-24-7; Benzo[b][1,4]oxazine-7-sulfonyl chloride, 3,4-dihydro-3-oxo-
EINECS	Contact for details

Quality Control

Our 3-Oxo-3,4-Dihydro-2H-Benzo[B][1,4]Oxazine-7-Sulfonyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when prolonged exposure is anticipated to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.