Description

2,4-Diphenyl-1,3-thiazole-5-sulfonyl chloride is a specialized heterocyclic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its high reactivity as a sulfonylation reagent, enabling the efficient introduction of the 2,4-diphenylthiazole moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting specific enzymes or receptors where the 2,4-diphenylthiazole scaffold is pharmacologically active.
• Agrochemical Research: Used in creating novel herbicides, fungicides, or insecticides by acting as a sulfonylation agent to modify lead compounds.
• Material Science: Building block for synthesizing specialty polymers, liquid crystals, or organic electronic materials that require the incorporation of a rigid, conjugated thiazole unit.
• Chemical Biology & Proteomics: Potential use as a reactive handle for labeling or modifying biomolecules (proteins, peptides) in activity-based protein profiling (ABPP) studies.
• Dye & Pigment Synthesis: Intermediate in the production of specialized dyes and fluorescent tags due to the chromophoric nature of the diphenylthiazole core.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research and development projects requiring this specific sulfonyl chloride functionality.

Basic Information

Item	Detail
Product Name	2,4-Diphenyl-1,3-thiazole-5-sulfonyl Chloride
CAS No.	868755-57-1
Molecular Formula	C15H10ClNO2S2
Molecular Weight	335.83 g/mol
Synonyms	5-(Chlorosulfonyl)-2,4-diphenyl-1,3-thiazole; 2,4-Diphenylthiazole-5-sulfonyl chloride; 1,3-Thiazole, 2,4-diphenyl-, 5-sulfonyl chloride; 868755-57-1; 2,4-Diphenyl-1,3-thiazol-5-ylsulfonyl chloride; 5-Chlorosulfonyl-2,4-diphenylthiazole; 2,4-DPTSC
EINECS	Contact for details

Quality Control

Our 2,4-Diphenyl-1,3-thiazole-5-sulfonyl chloride is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity, suitable for demanding research and scale-up applications. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry for comprehensive characterization. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.