Description

2-Chloro-5-(Chlorosulfonyl)-4-Fluoro-Benzoyl Chloride is a highly reactive and versatile chemical intermediate, crucial for introducing complex aromatic functionalities into target molecules. Its value lies in its trifunctional nature, containing both a reactive benzoyl chloride and a chlorosulfonyl group, enabling precise synthesis of advanced compounds. This product is essential for R&D chemists and process engineers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of sulfonamide-based drugs and other complex heterocycles.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where its fluorinated aromatic structure contributes to biological activity and stability.
• Dyestuff and Pigment Manufacturing: Serves as a precursor for high-performance dyes and pigments, leveraging the chlorosulfonyl group for covalent bonding to polymers or other substrates.
• Polymer Modification: Acts as a functional monomer or cross-linking agent to introduce specific aromatic and sulfonyl groups into polymer chains, enhancing material properties.
• Organic Synthesis Reagent: Employed in research laboratories for the controlled introduction of acyl and sulfonyl chloride groups in multi-step synthetic routes.
• Liquid Crystal and Electronic Material Precursor: Used in the synthesis of specialized organic compounds for electronic applications, including liquid crystal displays (LCDs).

Basic Information

Item	Detail
Product Name	2-Chloro-5-(Chlorosulfonyl)-4-Fluoro-Benzoyl Chloride
CAS No.	866763-17-9
Molecular Formula	C7H2Cl2FO3S
Molecular Weight	271.06 g/mol
Synonyms	4-Fluoro-2-chloro-5-(chlorosulfonyl)benzoyl chloride; 2-Chloro-4-fluoro-5-sulfonylchloride benzoyl chloride; Benzoyl chloride, 2-chloro-5-(chlorosulfonyl)-4-fluoro-; 5-(Chlorosulfonyl)-2-chloro-4-fluorobenzoic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-(Chlorosulfonyl)-4-Fluoro-Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR, to ensure it meets the high standards required for advanced synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for our global B2B clients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Assay	97.0% - 102.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.