Description

Dodeca 2E,4E,8Z,10E,Z-Tetraenoic Acid Isobutylamide is a specialized synthetic analog of natural pungent compounds, valued for its potent and targeted bioactivity. This high-purity synthetic intermediate is critical for researchers and manufacturers requiring precise molecular structures for advanced applications. It serves as a key building block in the development of novel agrochemicals, pharmaceuticals, and sensory agents for the global life sciences and specialty chemical industries.

Application

• Agrochemical Research & Development: As a synthetic analog of natural insecticidal/pungent agents (e.g., from *Piper* species), it is used in the development of new-generation, bio-inspired crop protection agents and insect repellents.
• Pharmaceutical Intermediates: Serves as a crucial synthetic precursor or pharmacophore in medicinal chemistry programs targeting transient receptor potential (TRP) channels, particularly for pain management and anti-inflammatory drug discovery.
• Neuroscience & Sensory Biology: A valuable research tool (bioprobe) for studying TRPV1 and TRPA1 receptor activation mechanisms, aiding in the understanding of chemesthesis, pain pathways, and thermal sensation.
• Flavor & Fragrance Industry: Used in trace amounts to study and replicate pungent, "hot," or tingling sensory notes for creating complex flavor profiles or functional fragrance compounds.
• Chemical Synthesis: Acts as a versatile building block for the synthesis of more complex polyene amides and other derivatives with tailored biological or physical properties.
• Cosmetic & Personal Care Actives: Investigated for potential use in topical formulations designed to provide warming or cooling sensations, or as an active in functional cosmetic products.

Basic Information

Product Name	Dodeca 2E,4E,8Z,10E,Z-Tetraenoic Acid Isobutylamide
CAS No.	866602-52-0
Molecular Formula	C16H27NO
Molecular Weight	249.39 g/mol
Synonyms	(2E,4E,8Z,10E)-N-(2-Methylpropyl)dodeca-2,4,8,10-tetraenamide; Dodecatetraenoic Acid Isobutylamide; Synthetic Pungent Amide Analog; TRPV1/TRPA1 Agonist Probe; Isobutylamide of 2E,4E,8Z,10E-Dodecatetraenoic Acid; (E,E,Z,E)-N-Isobutyl-2,4,8,10-dodecatetraenamide
EINECS	Contact for details

Quality Control

Our Dodeca 2E,4E,8Z,10E,Z-Tetraenoic Acid Isobutylamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and MS for structural confirmation, and chiral analysis where applicable, to ensure identity, purity, and batch-to-batch consistency for research and development purposes. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere (e.g., nitrogen or argon) at temperatures of -20°C or below to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (IR)	Spectrum matches reference
Purity (HPLC)	≥ 95.0% (Area %)
Isomeric Purity (HPLC)	≥ 98.0% (2E,4E,8Z,10E isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.