Description

5-(2-(Trifluoromethyl)Phenyl)Oxazole is a specialized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluoromethylphenyl moiety imparts desirable metabolic stability and lipophilicity. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• As a crucial synthetic intermediate in pharmaceutical research for the development of new drug candidates.
• Utilized in the synthesis of agrochemicals, including potential herbicides and fungicides.
• Serves as a building block for advanced materials, such as organic light-emitting diodes (OLEDs) and liquid crystals.
• Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Applicable in academic and institutional research exploring novel heterocyclic chemistry and catalysis.
• Potential use in the development of fluorescent probes and imaging agents due to the oxazole core.

Basic Information

Product Name	5-(2-(Trifluoromethyl)Phenyl)Oxazole
CAS No.	866149-85-1
Molecular Formula	C10H6F3NO
Molecular Weight	213.16 g/mol
Synonyms	5-[2-(Trifluoromethyl)phenyl]-1,3-oxazole; 2-(5-Oxazolyl)benzotrifluoride; 5-(2-Trifluoromethylphenyl)oxazole; 5-(α,α,α-Trifluoro-o-tolyl)oxazole; Oxazole, 5-[2-(trifluoromethyl)phenyl]-
EINECS	Contact for details

Quality Control

Our 5-(2-(Trifluoromethyl)Phenyl)Oxazole is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent quality suitable for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.