Description

2-Fluoro-4-Methylphenyl Isothiocyanate is a versatile and reactive aromatic isothiocyanate derivative. This compound serves as a critical building block in organic synthesis, enabling the introduction of the thiourea pharmacophore into target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor for synthesizing thiourea and guanidine derivatives with potential biological activity.
• Agrochemical Research: Building block for developing new herbicides, fungicides, and insecticides.
• Chemical Biology Probe: Used to modify proteins and peptides via selective reactions with amino groups.
• Material Science: Monomer or cross-linking agent in the synthesis of specialized polymers and resins.
• Ligand Synthesis: Preparation of novel ligands for catalysis and metal complexation studies.

Basic Information

Product Name	2-Fluoro-4-Methylphenyl Isothiocyanate
CAS No.	864350-17-4
Molecular Formula	C8H6FNS
Molecular Weight	167.20 g/mol
Synonyms	2-Fluoro-4-methylphenyl isothiocyanate; 2-Fluoro-p-tolyl isothiocyanate; 1-Fluoro-2-isothiocyanato-4-methylbenzene; 4-Methyl-2-fluorophenyl isothiocyanate; Isothiocyanic acid, 2-fluoro-4-methylphenyl ester; 2-Fluoro-4-methylbenzenisothiocyanate
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methylphenyl Isothiocyanate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and impurity profiles against our stringent specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.