Description

(5-Fluoropyridin-3-Yl)Methanamine Hydrochloride is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in providing a functionalized amine handle on a fluorinated heterocyclic core, enabling the development of novel compounds with targeted biological activity. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluoropyridine moiety enhances bioavailability and stability.
• Chemical Biology & Proteomics: Employed as a versatile linker or labeling reagent in probe development for studying biological systems.
• Material Science Research: Acts as a precursor for functionalized ligands in catalyst design and for creating novel organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	(5-Fluoropyridin-3-Yl)Methanamine Hydrochloride
CAS No.	864263-69-4
Molecular Formula	C6H8ClFN2
Molecular Weight	162.59 g/mol
Synonyms	1-(5-Fluoropyridin-3-yl)methanamine hydrochloride; 3-(Aminomethyl)-5-fluoropyridine hydrochloride; (5-Fluoro-3-pyridinyl)methanamine hydrochloride; 5-Fluoro-3-pyridinemethanamine hydrochloride; 3-Pyridinemethanamine, 5-fluoro-, hydrochloride; 5-Fluoro-3-(aminomethyl)pyridine HCl; 3-Aminomethyl-5-fluoropyridine hydrochloride
EINECS	Contact for details

Quality Control

Our (5-Fluoropyridin-3-Yl)Methanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment. Our production can align with research-grade through to cGMP standards to support development and commercial-scale requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.