Description

Casein Kinase II Inhibitor IV is a potent and selective small molecule inhibitor of the CK2 protein kinase, a key regulator of numerous cellular processes. This compound is an essential research tool for investigating signaling pathways related to cell proliferation, survival, and DNA damage response. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies engaged in oncology, neurology, and fundamental cell biology studies.

Application

• Biochemical Research: Used as a selective probe to study the role of CK2 in signal transduction pathways and cellular function.
• Drug Discovery & Development: Serves as a lead compound or reference standard in screening assays for developing novel CK2-targeted therapeutics.
• Oncology Research: Investigates the inhibition of CK2 for its potential anti-cancer effects, as CK2 is often overexpressed in various tumors.
• Neuroscience Studies: Explores the involvement of CK2 in neurological disorders and neuronal signaling mechanisms.
• Cell Cycle Analysis: Applied in studies to understand CK2's regulation of the cell cycle and apoptosis.
• In Vitro & Cellular Assays: Employed in enzyme inhibition assays and cell-based experiments to determine potency and specificity.

Basic Information

Product Name	Casein Kinase II Inhibitor IV
CAS No.	863598-09-8
Molecular Formula	C₂₀H₁₉N₅O₂
Molecular Weight	361.40 g/mol
Synonyms	CK2 Inhibitor IV; 2-(3-(3,5-Dimethyl-1H-pyrazol-1-yl)phenylamino)-5,6,7,8-tetrahydroquinazolin-4(3H)-one; 5,6,7,8-Tetrahydro-2-[[3-(3,5-dimethyl-1H-pyrazol-1-yl)phenyl]amino]-4(3H)-quinazolinone; TBCA; Casein Kinase 2 Inhibitor IV
EINECS	Contact for details

Quality Control

Our Casein Kinase II Inhibitor IV is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity for research applications. All materials are subjected to comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing identity, purity, and assay results is provided with each shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. The product is light-sensitive (store away from light). Allow the vial to warm to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.