Description

Trpm2 Agonist-1 CAS NO 863238-55-5 is a potent and selective small molecule agonist for the Transient Receptor Potential Melastatin 2 (TRPM2) cation channel. This compound is a critical research tool for investigating the role of TRPM2 channels in physiological and pathological processes, including oxidative stress response, immune cell function, and neurological disorders. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on neurobiology, immunology, and drug discovery for related therapeutic areas.

Application

• Neuroscience Research: Used to study TRPM2 channel function in neurons, glial cells, and its implications in neurodegenerative diseases, stroke, and pain pathways.
• Immunology Studies: Applied in research on immune cell activation (e.g., monocytes, microglia) to understand inflammatory responses and autoimmune conditions.
• Drug Discovery & Screening: Serves as a reference standard and pharmacological tool in high-throughput screening assays to identify novel TRPM2 modulators.
• Cell Signaling Pathways: Employed to elucidate calcium signaling mechanisms mediated by TRPM2 channels under conditions of oxidative stress.
• Academic & Institutional Research: A key reagent for basic scientific research in university and institutional laboratories worldwide.

Basic Information

Product Name	Trpm2 Agonist-1
CAS No.	863238-55-5
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TRPM2 Agonist-1; TRPM2 Agonist 1; 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-chromen-4-one (related flavonoid core reference); Potential research code names may apply.
EINECS	Contact for details

Quality Control

Trpm2 Agonist-1 is manufactured under strict quality protocols to ensure batch-to-batch consistency and high purity for research applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards for research chemicals. Certificates of Analysis (COA) detailing purity, identity, and other critical parameters are available upon request to support your research documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed in a desiccated environment and away from light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.