Description

3-Iodo-2-Methylbenzotrifluoride is a high-value halogenated aromatic building block characterized by its trifluoromethyl and iodine substituents. This compound is essential for facilitating advanced cross-coupling reactions, enabling the precise synthesis of complex molecules in research and development. It is primarily sought after by pharmaceutical and agrochemical R&D teams, as well as specialty chemical manufacturers, for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry for creating fluorinated analogs.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Material Science: Serves as a precursor for functional materials, including liquid crystals and organic semiconductors, due to its unique electronic properties.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Stille, and Negishi couplings to form biaryl structures.
• Chemical Research: Employed in academic and industrial laboratories for method development and exploring new synthetic pathways.
• Ligand and Catalyst Development: Used to synthesize sophisticated ligands for catalysis and molecular recognition applications.

Basic Information

Product Name	3-Iodo-2-Methylbenzotrifluoride
CAS No.	863111-55-1
Molecular Formula	C8H6F3I
Molecular Weight	286.04 g/mol
Synonyms	2-Methyl-3-iodobenzotrifluoride; 1-Iodo-2-methyl-3-(trifluoromethyl)benzene; 3-Iodo-2-methyl-α,α,α-trifluorotoluene; 2-Methyl-α,α,α-trifluoro-3-iodotoluene; 3-Iodo-2-methylbenzylidynetrifluoride; 3-Iodo-2-(trifluoromethyl)toluene; 2-Methyl-3-(trifluoromethyl)iodobenzene
EINECS	Contact for details

Quality Control

Our 3-Iodo-2-Methylbenzotrifluoride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber glass or opaque.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.