Description

Ly2228820 is a high-purity, small-molecule chemical compound designed for advanced research and development. This compound is valued for its role as a potent and selective inhibitor in biochemical and pharmacological studies, enabling critical pathway analysis. It is primarily utilized by pharmaceutical R&D teams, biotechnology companies, and academic research institutions focused on oncology, immunology, and signal transduction research.

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and active pharmaceutical ingredient (API) intermediate in the discovery and development of novel therapeutic agents.
• Biochemical Assays: Used as a potent and selective tool compound in enzymatic and cellular assays to study specific biological pathways and target validation.
• Preclinical Studies: Employed in in vitro and in vivo studies to investigate efficacy, pharmacokinetics, and mechanism of action for potential drug candidates.
• Academic Research: A critical reagent for universities and research institutes exploring cellular signaling mechanisms, particularly in fields like oncology and immunology.
• Chemical Synthesis: Acts as a sophisticated building block or intermediate for the synthesis of more complex molecules in medicinal chemistry programs.
• Quality Control & Analytical Standards: Provides a high-purity standard for analytical method development, validation, and quality control testing in GMP and non-GMP environments.

Basic Information

Product Name	Ly2228820
CAS No.	862505-00-8
Molecular Formula	C₂₀H₂₀N₄O₃
Molecular Weight	364.40 g/mol
Synonyms	LY-2228820; 1-(4-(4-Morpholinyl)phenyl)-9H-pyrido[3,4-b]indol-3-amine; 9H-Pyrido[3,4-b]indol-3-amine, 1-[4-(4-morpholinyl)phenyl]-; Ruxolitinib analog; JAK inhibitor (research compound); Kinase inhibitor LY2228820; 862505-00-8 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our Ly2228820 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with customer specifications and relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	<20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.