Description

Protein Kinase C Beta II Peptide Inhibitor I Trifluoroacetate Salt is a potent and selective cell-permeable peptide inhibitor designed to target the PKCβII isoform. This compound is a critical research tool for elucidating the specific roles of PKCβII in cellular signaling pathways, particularly those related to immune response, angiogenesis, and neurological function. It is essential for academic researchers, pharmaceutical R&D teams, and biotechnology companies engaged in kinase biology, drug discovery, and the development of targeted therapeutics for conditions like cancer, diabetic complications, and inflammatory diseases.

Application

• Biochemical Research: Used as a selective tool compound to study the specific functions and signaling mechanisms of Protein Kinase C beta II (PKCβII) in vitro.
• Drug Discovery & Target Validation: Serves as a key pharmacological probe in high-throughput screening (HTS) campaigns and target validation studies for oncology and metabolic disorder pipelines.
• Cell Signaling Pathway Analysis: Enables the dissection of complex signaling networks in cell-based assays, helping to identify downstream effects of PKCβII inhibition.
• Academic & Preclinical Studies: Facilitates fundamental research in areas such as angiogenesis, immune cell activation, and neuronal plasticity in laboratory models.
• Pharmaceutical Development: Supports lead optimization and mechanism-of-action studies for developing novel PKCβII-targeted inhibitors.

Basic Information

Product Name	Protein Kinase C Beta II Peptide Inhibitor I Trifluoroacetate Salt
CAS No.	862502-26-9
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PKCβII Inhibitor I; PKC beta II Peptide Inhibitor I; PKCβII Pseudosubstrate Inhibitor; Myristoylated PKCβII Inhibitor; PKCβII (V5-3) Inhibitor; Cell-permeable PKCβII Inhibitor; CAS 862502-26-9
EINECS	Contact for details

Quality Control

Our Protein Kinase C Beta II Peptide Inhibitor I Trifluoroacetate Salt is manufactured under strict quality protocols suitable for research applications. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability, batch-to-batch consistency, and compliance with the specifications required for sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Solubility	Soluble in DMSO, slightly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.