Description

Necrosis Inhibitor, Im-54 is a potent, cell-permeable small molecule inhibitor specifically designed to target and modulate key pathways involved in programmed cell death. This compound is of significant value for research and development in life sciences, offering a critical tool for studying cellular mechanisms and developing therapeutic interventions. It is primarily needed by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on oncology, neurobiology, and inflammatory disease models.

Application

• Biomedical Research: A key reagent for investigating the molecular mechanisms of necrosis and related cell death pathways in vitro and in vivo.
• Drug Discovery & Development: Used as a pharmacological tool in high-throughput screening (HTS) and target validation studies for novel therapeutic candidates.
• Preclinical Studies: Employed in animal models to evaluate the protective effects against tissue damage in conditions like ischemia-reperfusion injury, stroke, or myocardial infarction.
• Academic Research: Essential for basic science studies in cell biology, biochemistry, and pathology departments to dissect cell death signaling networks.
• Biotech & Pharma R&D: Supports the development of treatments for diseases where uncontrolled necrosis is a pathological feature.

Basic Information

Product Name	Necrosis Inhibitor, Im-54
CAS No.	861891-50-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	IM-54; Necrosis Inhibitor IM-54; IM 54; Inhibitor of Necrosis IM-54; 1H-Pyrrole-2,5-dione, 1-[(4-bromophenyl)methyl]-3-methyl-; 1-[(4-Bromobenzyl)]-3-methylmaleimide; 1-(4-Bromobenzyl)-3-methyl-1H-pyrrole-2,5-dione
EINECS	Contact for details

Quality Control

Our Necrosis Inhibitor, Im-54 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for research applications. A comprehensive Certificate of Analysis (COA) detailing purity, batch number, and analytical results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.