Description

5-Methoxy-2-Methylbenzenesulfonyl Chloride is a versatile and high-purity sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation agent, enabling the introduction of the sulfonyl functional group to construct complex molecular architectures. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for API synthesis and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of sulfonamide-based drugs.
• Agrochemical Synthesis: Used in the production of novel herbicides, fungicides, and pesticides where the sulfonyl moiety is a core functional group.
• Dye and Pigment Manufacturing: Acts as a reactant in the synthesis of sulfonated dyes and specialty colorants.
• Polymer Chemistry: Employed as a monomer or modifying agent to introduce sulfonyl groups into polymer chains, altering material properties.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D for exploring new synthetic pathways and creating compound libraries.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis.

Basic Information

Product Name	5-Methoxy-2-Methylbenzenesulfonyl Chloride
CAS No.	861374-10-9
Molecular Formula	C8H9ClO3S
Molecular Weight	220.67 g/mol
Synonyms	2-Methyl-5-methoxybenzenesulfonyl chloride; 5-Methoxy-o-toluenesulfonyl chloride; 1-Methoxy-4-methyl-3-sulfonylchloridobenzene; 3-Methyl-6-methoxybenzenesulfonyl chloride; 5-Methoxy-2-methylphenylsulfonyl chloride; 2-Methyl-5-methoxyphenylsulfonyl chloride; 5-Methoxy-2-toluenesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 5-Methoxy-2-Methylbenzenesulfonyl Chloride is manufactured under a strict quality management system. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, strong oxidizing agents, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.