Description

Methyl 2-(4-(Trifluoromethyl)Piperidin-1-Yl)Acetate CAS NO 860343-95-9 is a high-purity, functionalized piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the combination of the piperidine scaffold and the trifluoromethyl group, which are highly sought-after motifs for modulating the physicochemical and biological properties of target molecules. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

This versatile chemical intermediate is designed for sophisticated synthesis workflows. Its primary applications include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) drugs, receptor modulators, and other bioactive molecules where the piperidine and trifluoromethyl groups enhance metabolic stability and binding affinity.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group often contributes to improved efficacy and environmental profile.
• Chemical Research & Development: Serves as a valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Ligand and Catalyst Preparation: Can be utilized to synthesize novel ligands for catalysis or as a component in the development of specialty chemicals and materials.

Basic Information

Product Name	Methyl 2-(4-(Trifluoromethyl)Piperidin-1-Yl)Acetate
CAS No.	860343-95-9
Molecular Formula	C9H14F3NO2
Molecular Weight	225.21 g/mol
Synonyms	Methyl (4-(Trifluoromethyl)-1-piperidinyl)acetate; 1-Piperidineacetic acid, 4-(trifluoromethyl)-, methyl ester; Methyl 2-[4-(trifluoromethyl)piperidin-1-yl]acetate; 2-(4-(Trifluoromethyl)piperidin-1-yl)acetic acid methyl ester; 860343-95-9; Methyl 4-(trifluoromethyl)-1-piperidineacetate
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(4-(Trifluoromethyl)Piperidin-1-Yl)Acetate adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and supporting regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.