Description

2-Pyridinemethanamine, 4-Fluoro- is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in enabling the precise introduction of both a fluorine atom and a primary amine functional group onto a pyridine scaffold, which is essential for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infective agents.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atom enhances metabolic stability and bioavailability.
• Ligand Synthesis: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Fluorinated Building Block: Employed in the synthesis of complex fluorinated heterocycles and fine chemicals for material science applications.
• Bioconjugation & Probe Development: The primary amine group facilitates conjugation reactions, making it useful for creating fluorescent probes or biochemical tools.

Basic Information

Product Name	2-Pyridinemethanamine, 4-Fluoro-
CAS No.	859166-87-3
Molecular Formula	C6H7FN2
Molecular Weight	126.13 g/mol
Synonyms	4-Fluoro-2-(aminomethyl)pyridine; (4-Fluoropyridin-2-yl)methanamine; 2-(Aminomethyl)-4-fluoropyridine; 4-Fluoro-2-pyridinemethanamine; 4-Fluoro-2-picolylamine; 2-Pyridinemethanamine, 4-fluoro-; 4-Fluoro-2-(aminomethyl)pyridine; 4-Fluoro-α-picolylamine
EINECS	Contact for details

Quality Control

Our 2-Pyridinemethanamine, 4-Fluoro- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Assay	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.