Description

Kynurenic Acid, 3-Methyl- (4Ci) is a methylated derivative of the endogenous tryptophan metabolite kynurenic acid, representing a key intermediate and reference standard in neurochemical research. This compound is valued for its role in studying the kynurenine pathway, which is critically involved in neurological function and immune modulation. It is primarily utilized by research scientists and development chemists in the pharmaceutical, biotechnology, and academic sectors for target validation, assay development, and metabolic pathway analysis.

Application

• Neurological Research: Used as a reference standard and tool compound to investigate the kynurenine pathway's role in neuroprotection, neurotoxicity, and associated disorders.
• Pharmaceutical R&D: Serves as a critical intermediate or analytical standard in the discovery and development of novel therapeutics targeting metabolic and neurological diseases.
• Biochemical Assay Development: Employed in the development and validation of high-throughput screening (HTS) assays and analytical methods (e.g., HPLC, LC-MS) for metabolite quantification.
• Academic Research: Utilized in university and institutional labs for fundamental studies on tryptophan metabolism, receptor interactions, and cellular signaling pathways.
• Metabolite Standard: Acts as a certified reference material (CRM) for the accurate calibration and quality control of analytical instrumentation in bioanalytical laboratories.

Basic Information

Product Name	Kynurenic Acid, 3-Methyl- (4Ci)
CAS No.	858488-66-1
Molecular Formula	C11H9NO4
Molecular Weight	219.19 g/mol
Synonyms	3-Methylkynurenic Acid; 3-Methyl-4-hydroxyquinoline-2-carboxylic Acid; 4-Hydroxy-3-methylquinoline-2-carboxylic Acid; 3-Methyl-KYNA; 3-Me-KYNA; 3-Methylquinolinic Acid (ambiguous, not preferred); 3-Methylkynurenate
EINECS	Contact for details

Quality Control

Our Kynurenic Acid, 3-Methyl- (4Ci) is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity confirmation and spectroscopic methods (NMR, MS) for structural verification, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic and spectral data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.