Description

2-Ethoxy-4-(Trifluoromethyl)Pyridine is a high-value, multi-functional heterocyclic building block characterized by its pyridine core substituted with an ethoxy group and a trifluoromethyl group. This compound matters for its unique electronic properties and stability imparted by the fluorine atoms, making it a critical intermediate in advanced synthesis. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients, particularly where enhanced metabolic stability and lipophilicity are desired.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, especially for kinase inhibitors, antiviral agents, and central nervous system (CNS) active compounds.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in catalysis, particularly in cross-coupling and other transition metal-catalyzed reactions.
• Material Science Research: Employed in the development of organic electronic materials, such as components for organic light-emitting diodes (OLEDs) or conductive polymers.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying biological processes due to its potential for selective binding and labeling.

Basic Information

Product Name	2-Ethoxy-4-(Trifluoromethyl)Pyridine
CAS No.	858421-08-6
Molecular Formula	C8H8F3NO
Molecular Weight	191.15 g/mol
Synonyms	4-(Trifluoromethyl)-2-ethoxypyridine; 2-Ethoxy-4-trifluoromethylpyridine; 2-Ethoxy-α,α,α-trifluoro-picoline; Pyridine, 2-ethoxy-4-(trifluoromethyl)-; 858421-08-6
EINECS	Contact for details

Quality Control

Our 2-Ethoxy-4-(Trifluoromethyl)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to cGMP and ISO standards ensures reliable supply for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.