Description

Retaspimycin is a potent ansamycin antibiotic and a promising investigational agent in the field of oncology. Its core value proposition lies in its targeted mechanism of action, which is of significant interest for advanced therapeutic research and development. This compound is primarily needed by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on developing novel cancer therapies and studying heat shock protein 90 (Hsp90) inhibition.

Application

• Oncology Research: As a potent Hsp90 inhibitor for investigating novel cancer treatment pathways and combination therapies.
• Pharmaceutical Development: Serves as a key active pharmaceutical ingredient (API) or intermediate in the preclinical and clinical development of targeted cancer drugs.
• Biochemical Research: Used as a selective tool compound in molecular biology to study protein folding, client protein degradation, and chaperone function.
• Mechanism of Action Studies: Employed in pharmacological assays to understand the downstream effects of Hsp90 inhibition on oncogenic signaling pathways.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Item	Details
Product Name	Retaspimycin
CAS No.	857402-23-4
Molecular Formula	C31H43N3O8
Molecular Weight	585.70 g/mol
Synonyms	IPI-504; Hydroquinone Hydrochloride, 17-Allylamino-17-demethoxygeldanamycin; 17-AAG Hydroquinone Hydrochloride; 17-(Allylamino)-17-demethoxygeldanamycin hydroquinone hydrochloride; Tanespimycin Hydroquinone Hydrochloride; Retaspimycin Hydrochloride; Hsp90 Inhibitor IPI-504
EINECS	Contact for details

Quality Control

Our Retaspimycin is manufactured under strict quality systems to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research-grade chemicals, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature, typically between 15-25°C, in a dry environment. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	Off-white to tan solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.