Description

7-Iodo-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride is a high-value, multi-functional chemical building block primarily used in advanced organic synthesis. Its core value lies in the reactive sulfonyl chloride and halogenated benzofuran moieties, enabling it to serve as a key intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of potential drug candidates, especially those targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the benzofuran scaffold for bioactivity.
• Material Science: Serves as a monomer or cross-linking agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology & Proteomics: The sulfonyl chloride group is utilized for selective labeling, bioconjugation, and as an activity-based probe in protein studies.
• Organic Synthesis Reagent: Acts as a versatile electrophile in cross-coupling reactions (e.g., Suzuki, Sonogashira) and for introducing the sulfonamide functional group.

Basic Information

Product Name	7-Iodo-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride
CAS No.	856678-57-4
Molecular Formula	C8H6ClIO3S
Molecular Weight	344.55 g/mol
Synonyms	5-Sulfonylchloride-7-iodo-2,3-dihydrobenzofuran; 7-Iodo-2,3-dihydrobenzofuran-5-sulfonyl chloride; 2,3-Dihydro-7-iodobenzofuran-5-sulfonyl chloride; 7-Iododihydrobenzofuran-5-sulfonyl chloride; Benzofuran-5-sulfonyl chloride, 7-iodo-2,3-dihydro-; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Every batch of 7-Iodo-2,3-Dihydrobenzofuran-5-Sulfonyl Chloride is produced and tested under a strict quality management system. We ensure high purity and consistency through advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.