Description

Jak3 Inhibitor Vi CAS NO 856436-16-3 is a potent and selective small molecule inhibitor targeting the Janus kinase 3 (JAK3) signaling pathway. This compound is a critical research tool for investigating the role of JAK3 in immune cell function and inflammatory disease mechanisms. It is primarily utilized by pharmaceutical R&D teams, academic researchers, and biotechnology companies focused on immunology and autoimmune disease drug discovery.

Application

• Biochemical Research: Used as a selective inhibitor to study JAK-STAT signaling pathways in cellular assays.
• Drug Discovery & Development: Serves as a key reference compound or lead molecule in the development of novel immunomodulatory therapeutics.
• In Vitro Pharmacology: Employed in high-throughput screening (HTS) and target validation studies for autoimmune and inflammatory conditions.
• Mechanistic Studies: Facilitates the investigation of JAK3's role in lymphocyte activation, proliferation, and function.
• Academic Research: A standard reagent for university and institutional labs exploring cytokine signaling and immune regulation.

Basic Information

Product Name	Jak3 Inhibitor Vi CAS NO 856436-16-3
CAS No.	856436-16-3
Molecular Formula	C₂₀H₂₀N₆O₂
Molecular Weight	376.41 g/mol
Synonyms	JAK3 Inhibitor VI; (3R,4R)-3-[(4-Methylphenyl)sulfonyl]-4-(phenylacetyl)amino-1-(phenylmethyl)-2-pyrrolidinone; CP-690,550 analog; Tofacitinib analog; JAK3 Inhibitor; Janus Kinase 3 Inhibitor VI; 1-Benzyl-3-[(4-methylphenyl)sulfonyl]-4-[(phenylacetyl)amino]-3-pyrrolidinol
EINECS	Contact for details

Quality Control

Our Jak3 Inhibitor Vi is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure high chemical integrity and batch-to-batch consistency. Certificates of Analysis (COA) with detailed specifications are provided to support your research and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccated conditions. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.