Description

5-Fluoro-6-Methoxypyridine-3-Boronic Acid is a high-value boronic acid derivative and a key building block in modern synthetic chemistry. Its primary value lies in enabling the efficient construction of complex molecules through pivotal cross-coupling reactions, such as the Suzuki-Miyaura reaction. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and reliable intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing fluorinated pyridine scaffolds.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides that benefit from the stability and reactivity of the boronic acid group.
• Suzuki-Miyaura Cross-Coupling: Serves as a versatile boron reagent for forming carbon-carbon bonds, essential for creating complex biaryl and heterobiaryl structures in medicinal chemistry.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands and organometallic catalysts for asymmetric synthesis and other catalytic processes.
• Material Science Research: Acts as a building block for constructing organic electronic materials, such as those used in OLEDs and organic semiconductors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and inhibitors for target identification and validation in biological systems.

Basic Information

Product Name	5-Fluoro-6-Methoxypyridine-3-Boronic Acid
CAS No.	856250-60-7
Molecular Formula	C6H7BFNO3
Molecular Weight	170.94 g/mol
Synonyms	(5-Fluoro-6-methoxypyridin-3-yl)boronic acid; 5-Fluoro-6-methoxy-3-pyridineboronic acid; 3-Borono-5-fluoro-6-methoxypyridine; 5-Fluoro-6-methoxy-3-pyridinylboronic acid; Boronic acid, B-(5-fluoro-6-methoxy-3-pyridinyl)-; 856250-60-7
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methoxypyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.