Description

(Naphthalen-4-Yl)Methanesulfonyl Chloride is a specialized organic sulfonyl chloride derivative, serving as a critical building block in advanced chemical synthesis. Its core value lies in its high reactivity as an electrophile, enabling the efficient introduction of the (naphthalen-4-yl)methanesulfonyl moiety into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials. Its precise structure offers unique steric and electronic properties for creating complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of potential drug candidates, particularly for creating sulfonamide-based compounds with targeted biological activity.
• Agrochemical Research: Used in developing new herbicides, fungicides, and insecticides by acting as a sulfonylation agent for bioactive molecules.
• Material Science: Building block for synthesizing specialized polymers, ligands, or organic semiconductors where the naphthalene sulfonyl group modifies material properties.
• Chemical Biology & Proteomics: Potential use as a reactive handle for labeling or modifying proteins and other biomolecules in research settings.
• Organic Synthesis: Versatile electrophile for constructing carbon-sulfur bonds in complex multi-step synthetic routes for fine chemicals.

Basic Information

Product Name	(Naphthalen-4-Yl)Methanesulfonyl Chloride
CAS No.	856199-38-7
Molecular Formula	C11H9ClO2S
Molecular Weight	240.70 g/mol
Synonyms	4-(Chlorosulfonylmethyl)naphthalene; 1-(Chlorosulfonylmethyl)naphthalene; p-Naphthylmethanesulfonyl chloride; 4-Naphthylmethanesulfonyl chloride; (4-Naphthyl)methanesulfonyl chloride; Naphthalene-4-methanesulfonyl chloride; 856199-38-7; (Naphthalen-4-yl)methanesulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of (Naphthalen-4-Yl)Methanesulfonyl Chloride is produced and tested under strict quality management protocols to ensure consistency and reliability for research and development. Our products undergo rigorous quality testing, including chromatographic purity analysis and identity confirmation, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific data are available upon request, providing full traceability and supporting your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from incompatible materials such as strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.