Description

1,2-Benzenedicarboxaldehyde, 4,5-Difluoro- is a high-purity, fluorinated aromatic dialdehyde building block of significant interest in advanced organic synthesis. Its value lies in its dual aldehyde functionality and strategic fluorine substitution, enabling precise molecular construction for complex target molecules. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries seeking to incorporate a difluorinated phthalaldehyde core into their products.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for fluorinated drug candidates targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in developing advanced herbicides, fungicides, and pesticides where the fluorine atoms enhance biological activity, stability, and metabolic resistance.
• Ligand and Chelator Preparation: Serves as a starting material for synthesizing sophisticated Schiff base ligands and macrocyclic chelators used in catalysis and metal ion sequestration.
• Polymer and Material Science: Employed in the creation of novel fluorinated polymers, dendrimers, and organic frameworks (e.g., MOFs, COFs) with tailored thermal, optical, or surface properties.
• Chemical Research & Development: A versatile scaffold in medicinal chemistry and material science R&D for structure-activity relationship (SAR) studies and library synthesis.
• Fluorescent Probe and Sensor Development: Utilized in the design of fluorogenic probes and chemosensors due to its reactive aldehyde groups and fluorophore precursor potential.

Basic Information

Product Name	1,2-Benzenedicarboxaldehyde, 4,5-Difluoro-
CAS No.	854519-98-5
Molecular Formula	C8H4F2O2
Molecular Weight	170.11 g/mol
Synonyms	4,5-Difluorophthalaldehyde; 4,5-Difluorobenzene-1,2-dicarboxaldehyde; 4,5-Difluoro-1,2-benzenedicarboxaldehyde; 4,5-Difluoroisophthalaldehyde; 1,2-Diformyl-4,5-difluorobenzene; DFPAL; 4,5-DFPA
EINECS	Contact for details

Quality Control

Every batch of 1,2-Benzenedicarboxaldehyde, 4,5-Difluoro- is manufactured and analyzed under strict quality management systems. We ensure high purity and consistency through advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents, strong bases, and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.