Description

7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-Methyl-1-Nonenyl]-5-Oxo-3-Cyclopenten-1-Yl]-2-Heptenoic Acid is a high-purity, stereochemically defined prostaglandin analog with significant biological activity. This compound is critical for advanced pharmaceutical research and development, particularly in the study of prostanoid receptors and their physiological pathways. It serves as a key synthetic intermediate or reference standard for researchers in drug discovery, medicinal chemistry, and life sciences, enabling the development of novel therapeutics targeting inflammation, cardiovascular function, and other critical biological processes.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel prostaglandin-based drug candidates and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard and probe in pharmacological studies to investigate the function and signaling of prostanoid receptors (DP, EP, FP, IP, TP).
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to optimize potency, selectivity, and metabolic stability of therapeutic agents.
• Life Science Reagent: Employed in cell-based assays and in vitro studies to elucidate pathways related to inflammation, smooth muscle contraction, and platelet aggregation.
• Process Development: Acts as a high-value intermediate in the scale-up and optimization of synthetic routes for prostaglandin manufacturing.
• Analytical Standard: Provides a certified reference material for quality control and method validation in analytical laboratories using HPLC, LC-MS, or NMR.

Basic Information

Product Name	7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-Methyl-1-Nonenyl]-5-Oxo-3-Cyclopenten-1-Yl]-2-Heptenoic Acid
CAS No.	853998-94-4
Molecular Formula	C22H34O4
Molecular Weight	362.50 g/mol
Synonyms	(5Z)-7-[(1R,2S,3R,5S)-2-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonen-1-yl]-5-oxo-3-cyclopenten-1-yl]-5-heptenoic acid; 7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-methyl-1-nonenyl]-5-oxocyclopent-3-en-1-yl]hept-2-enoic acid; Prostaglandin F2α analog; 13,14-Dihydro-15-keto Prostaglandin F2α derivative; PGF2α type compound; 9,11-Dideoxy-9α,11α-epoxymethano-PGF2α related intermediate; (Z)-7-[(1R,2S,3R,5S)-2-[(1E,3S,5S)-3-Hydroxy-5-methylnon-1-en-1-yl]-5-oxocyclopent-3-en-1-yl]hept-5-enoic acid
EINECS	Contact for details

Quality Control

Our 7-[(1R,2S)-2-[(1E,3S,5S)-3-Hydroxy-5-Methyl-1-Nonenyl]-5-Oxo-3-Cyclopenten-1-Yl]-2-Heptenoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure identity, potency, and purity meet the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided, documenting results for assay, related substances, residual solvents, and specific rotation. Our quality commitment aligns with cGMP principles for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., nitrogen or argon) to prevent oxidation. The container should be kept in a cool, dry, and well-ventilated area. Allow the product to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC, Total)	≥ 99.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.