Description

17-Methyl-5α-Androstane-3β,17β-Diol-D5 is a high-purity, deuterium-labeled analog of a key steroid intermediate. This compound is specifically valued for its utility as an internal standard in analytical chemistry, ensuring precise quantification and method validation in complex matrices. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical service providers engaged in metabolism studies, pharmacokinetic research, and quality control of steroid-based pharmaceuticals.

Application

• Internal Standard for LC-MS/MS: Critical for accurate quantification in bioanalytical methods for steroid hormone analysis.
• Metabolite Tracing & Pharmacokinetics: Used in drug metabolism and disposition (DMPK) studies to track the fate of parent compounds.
• Reference Standard: Serves as a certified reference material (CRM) for calibrating analytical instruments and validating test methods.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of related substances in active pharmaceutical ingredients (APIs).
• Endocrine Research: Supports scientific investigations into steroid biosynthesis pathways and receptor interactions.
• Doping Control Analysis: Employed in sports anti-doping laboratories for the definitive detection of synthetic anabolic agents.

Basic Information

Product Name	17-Methyl-5α-Androstane-3β,17β-Diol-D5
CAS No.	853904-65-1
Molecular Formula	C20H31D5O2
Molecular Weight	307.52 g/mol (approx.)
Synonyms	17-Methylandrostane-3β,17β-diol-d5; (3β,5α,17β)-17-Methyl-5-androstane-3,17-diol-d5; Deuterated 17-Methyl-5α-Androstanediol; 17-Methyl-5α-dihydrotestosterone-d5 Diol; 17-Methyl-DHT-d5 Diol; 17-Methyl-5α-androstan-3β,17β-diol-d5; 17-Methyl-androstanediol-d5; Internal Standard for 17-Methyl Steroids
EINECS	Contact for details

Quality Control

Every batch of 17-Methyl-5α-Androstane-3β,17β-Diol-D5 is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and isotopic enrichment meet the stringent requirements for research and analytical use. Our quality assurance protocol includes advanced techniques such as NMR (for deuterium incorporation verification), HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.