Description

Wnt Agonist CAS NO 853220-52-7 is a potent and selective small molecule activator of the Wnt/β-catenin signaling pathway, a critical regulator of cell proliferation, differentiation, and stem cell maintenance. This compound is essential for researchers and developers in life sciences, offering a reliable tool for modulating key biological processes. It is primarily utilized in pharmaceutical R&D, academic research, and biotechnology for applications in regenerative medicine, oncology studies, and developmental biology research.

Application

• Pharmaceutical Research & Development: Used as a lead compound or tool molecule for investigating and developing novel therapeutics targeting tissue regeneration and cancer.
• Stem Cell Biology: Applied to activate Wnt signaling to maintain stem cell pluripotency, enhance self-renewal, and direct differentiation in culture systems.
• Oncology Studies: Employed in preclinical research to study the role of Wnt pathway activation in tumorigenesis, cancer cell proliferation, and metastasis.
• Regenerative Medicine: Investigated for its potential to promote bone formation, wound healing, and tissue repair mechanisms.
• Developmental Biology: Serves as a critical reagent for studying embryonic development and pattern formation where Wnt signaling plays a fundamental role.
• High-Throughput Screening (HTS): Used as a reference standard or positive control in cell-based assays designed to discover new Wnt pathway modulators.

Basic Information

Product Name	Wnt Agonist
CAS No.	853220-52-7
Molecular Formula	C19H14N4O3S
Molecular Weight	378.41 g/mol
Synonyms	WAY-316606; 6-[[2-[[4-(2,2-Dimethyl-1-oxopropyl)phenyl]amino]-5-pyrimidinyl]thio]-1-hexanol; Wnt Agonist 1; Wnt/β-catenin agonist; Wnt pathway activator 1; Wnt signaling activator; CAS 853220-52-7
EINECS	Contact for details

Quality Control

Our Wnt Agonist is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade standards. Specifications are designed to meet the stringent requirements of pharmaceutical and academic research applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and potency. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.