Description

4-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl chloride is a high-purity, reactive sulfonyl chloride derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in introducing the sulfonamide functional group, a key pharmacophore in medicinal chemistry. It is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of sulfonamide-based drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides that incorporate the sulfonamide moiety for enhanced bioactivity.
• Chemical Biology & Proteomics: Employed as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling (ABPP).
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers with specific sulfonyl functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	4-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl Chloride
CAS No.	852180-73-5
Molecular Formula	C10H8ClNO2S2
Molecular Weight	273.76 g/mol
Synonyms	4-(2-Methyl-4-thiazolyl)benzenesulfonyl chloride; 4-(2-Methylthiazol-4-yl)benzenesulfonyl chloride; 4-(2-Methyl-1,3-thiazol-4-yl)benzene-1-sulfonyl chloride; 852180-73-5; Benzenesulfonyl chloride, 4-(2-methyl-4-thiazolyl)-; 4-(2-Methyl-1,3-thiazol-4-yl)phenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 4-(2-Methyl-1,3-thiazol-4-yl)benzenesulfonyl chloride adheres to stringent internal quality standards to ensure batch-to-batch consistency and reliability for your synthetic workflows. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We support development from research to commercial scale with a commitment to quality that meets the expectations of the global pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.