Description

9H-Purin-6-Amine, 8-[(6-Bromo-1,3-Benzodioxol-5-Yl)Thio]-9-(4-Pentyn-1-Yl)- is a high-purity, advanced pharmaceutical intermediate designed for research and development in medicinal chemistry. This compound matters for its role as a key synthetic building block in the creation of novel therapeutic agents, particularly those targeting specific enzymatic pathways. Pharmaceutical R&D laboratories and fine chemical manufacturers need this material for developing next-generation drug candidates, especially in oncology and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel purine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new drug discovery programs.
• Biochemical Probe Development: Acts as a scaffold for creating tool compounds to study enzyme inhibition and cellular signaling pathways.
• Oncology Drug Discovery: Investigated for the development of targeted cancer therapies due to its modified purine structure.
• Antiviral Agent Synthesis: Explored as a building block for potential antiviral medications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	9H-Purin-6-Amine, 8-[(6-Bromo-1,3-Benzodioxol-5-Yl)Thio]-9-(4-Pentyn-1-Yl)-
CAS No.	852030-47-8
Molecular Formula	C₁₇H₁₄BrN₅O₂S
Molecular Weight	424.29 g/mol
Synonyms	8-((6-Bromo-1,3-benzodioxol-5-yl)thio)-9-(pent-4-yn-1-yl)-9H-purin-6-amine; 9-(4-Pentyn-1-yl)-8-[(6-bromo-1,3-benzodioxol-5-yl)thio]-9H-purin-6-amine; 852030-47-8; 8-[(6-Bromo-1,3-benzodioxol-5-yl)sulfanyl]-9-(pent-4-yn-1-yl)-9H-purin-6-amine; 9-(Pent-4-yn-1-yl)-8-((6-bromo-1,3-benzodioxol-5-yl)thio)-9H-purin-6-amine; 6-Amino-8-((6-bromo-1,3-benzodioxol-5-yl)thio)-9-(4-pentyn-1-yl)purine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch of 9H-Purin-6-Amine, 8-[(6-Bromo-1,3-Benzodioxol-5-Yl)Thio]-9-(4-Pentyn-1-Yl)- is analyzed using advanced chromatographic and spectroscopic techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are available upon request. We adhere to a cGMP-compliant quality management system suitable for pharmaceutical R&D applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment. For long-term storage, consider using desiccants and an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.