Description

n-[(2-Hydroxy-1-Hydroxymethyl)Ethyl]-11-Oxo-9Alpha,15S-Dihydroxy-Prosta-5Z, 13E-Dien-1-Amide is a high-purity synthetic prostaglandin derivative, a critical intermediate in advanced pharmaceutical research and development. This compound is valued for its precise stereochemistry and functional groups, which are essential for modulating biological pathways related to inflammation, cellular protection, and vascular function. It is primarily sought by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel prostaglandin-based drugs targeting ocular pressure, inflammation, and cytoprotection.
• Biochemical Research: Used as a reference standard or active agent in studies of prostanoid receptors (EP, FP, IP receptors) and their downstream signaling cascades.
• Cell Culture & In Vitro Studies: Employed to investigate its effects on cell proliferation, apoptosis, and inflammatory responses in specialized research models.
• Preclinical Development: Serves as a critical material for pharmacokinetic, pharmacodynamic, and toxicology studies during early drug candidate screening.
• Process Chemistry: Used in scaling up synthetic routes for prostaglandin analogs, requiring high chemical purity and isomeric fidelity.

Basic Information

Product Name	n-[(2-Hydroxy-1-Hydroxymethyl)Ethyl]-11-Oxo-9Alpha,15S-Dihydroxy-Prosta-5Z, 13E-Dien-1-Amide
CAS No.	851761-42-7
Molecular Formula	C23H37NO6
Molecular Weight	423.55 g/mol
Synonyms	11-Deoxy-16-hydroxy-17,18,19,20-tetranor-PGE2 ethanolamide; 11-Oxo-9α,15S-dihydroxy-prosta-5Z,13E-dien-1-oic acid, 2-[(2-hydroxy-1-hydroxymethyl)ethyl]amide; 16-Hydroxy-17,18,19,20-tetranor-PGE2 ethanolamide; 9α,15S-Dihydroxy-11-oxoprosta-5Z,13E-dien-1-oic acid (2-hydroxy-1-hydroxymethylethyl)amide; Prostaglandin E2 ethanolamide derivative; PGE2 ethanolamide analog; 11-Oxo-PGE2 ethanolamide
EINECS	Contact for details

Quality Control

Our n-[(2-Hydroxy-1-Hydroxymethyl)Ethyl]-11-Oxo-9Alpha,15S-Dihydroxy-Prosta-5Z, 13E-Dien-1-Amide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. Keep the container in a dry, well-ventilated area designated for laboratory chemicals.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.