Description

2-Chloro-5-Fluoro-Pyridine-3-Carbaldehyde is a high-purity, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound matters because its unique halogenated pyridine structure provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its halogenated pyridine core.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized organic molecules for electronic materials and liquid crystals.
• Custom Synthesis and Contract Manufacturing: A critical building block for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-5-Fluoro-Pyridine-3-Carbaldehyde
CAS No.	851484-95-2
Molecular Formula	C6H3ClFNO
Molecular Weight	159.54 g/mol
Synonyms	3-Formyl-2-chloro-5-fluoropyridine; 2-Chloro-5-fluoronicotinaldehyde; 2-Chloro-5-fluoropyridine-3-carboxaldehyde; 5-Fluoro-2-chloropyridine-3-carbaldehyde; 851484-95-2; 2-Chloro-5-fluoro-3-pyridinecarboxaldehyde; 2-Chloro-5-fluoronicotinyl aldehyde; 3-Pyridinecarboxaldehyde, 2-chloro-5-fluoro-
EINECS	Contact for details

Quality Control

Our 2-Chloro-5-Fluoro-Pyridine-3-Carbaldehyde is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high standards, including cGMP intermediates for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage and handling.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.