Description

3,6-Difluoro Pyridine-2-Carboxylic Acid is a high-value, multi-functional heterocyclic building block characterized by its carboxylic acid and fluorine substituents. This compound is essential for the synthesis of advanced pharmaceutical intermediates and agrochemicals, where its unique structure enables precise molecular modifications. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system and anti-infectives.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, fungicides, and insecticides, leveraging the fluorine atoms for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a versatile scaffold for constructing complex ligands used in metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Employed in the creation of specialty polymers and advanced organic electronic materials due to its electron-withdrawing properties.
• Chemical Biology Probes: Utilized as a building block for fluorinated probes and tags in medicinal chemistry and diagnostic assay development.

Basic Information

Product Name	3,6-Difluoro Pyridine-2-Carboxylic Acid
CAS No.	851386-45-3
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	2,5-Difluoropyridine-6-carboxylic Acid; 2-Carboxy-3,6-difluoropyridine; 3,6-Difluoropicolinic Acid; 3,6-Difluoro-2-pyridinecarboxylic Acid; 6-Fluoro-2-pyridinecarboxylic Acid, 3-fluoro- derivative; Picolinic acid, 3,6-difluoro-; 851386-45-3
EINECS	Contact for details

Quality Control

Our 3,6-Difluoro Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) documenting all critical quality attributes are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.