Description

2,3-Difluoropyridine-4-Carboxylic Acid is a high-purity fluorinated pyridine derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for precise structural modifications in target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the difluoropyridine moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and electronic materials requiring specific fluorine substitution.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2,3-Difluoropyridine-4-Carboxylic Acid
CAS No.	851386-31-7
Molecular Formula	C6H3F2NO2
Molecular Weight	159.09 g/mol
Synonyms	4-Carboxy-2,3-difluoropyridine; 2,3-Difluoropyridine-4-carboxylic acid; 2,3-Difluoroisonicotinic acid; 2,3-Difluoro-4-pyridinecarboxylic acid; 851386-31-7; 4-Pyridinecarboxylic acid, 2,3-difluoro-; Difluoropyridinecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2,3-Difluoropyridine-4-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and oxidizing agents. For long-term storage, consider inert atmosphere conditions to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.