Description

(3-[4-(Trifluoromethyl)Phenyl]-1,2,4-Thiadiazol-5-Yl)Methanol is a high-value, fluorinated heterocyclic building block characterized by its unique thiadiazole core and trifluoromethylphenyl moiety. This compound matters as a critical intermediate for advanced research and development, offering a versatile scaffold for introducing specific physicochemical properties into target molecules. It is primarily needed by pharmaceutical, agrochemical, and advanced material scientists engaged in the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in areas targeting CNS disorders, inflammation, and oncology.
• Agrochemical Research: Serves as a building block for novel herbicides, fungicides, and insecticides, leveraging the bioactivity-enhancing properties of the thiadiazole and trifluoromethyl groups.
• Material Science Precursor: Used in the synthesis of specialty polymers, liquid crystals, and organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probe: Employed in the design and synthesis of molecular probes and enzyme inhibitors for biochemical pathway analysis.
• Custom Synthesis & Contract Manufacturing: An essential starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	(3-[4-(Trifluoromethyl)Phenyl]-1,2,4-Thiadiazol-5-Yl)Methanol
CAS No.	851224-81-2
Molecular Formula	C10H7F3N2OS
Molecular Weight	260.24 g/mol
Synonyms	5-(Hydroxymethyl)-3-[4-(trifluoromethyl)phenyl]-1,2,4-thiadiazole; [4-(Trifluoromethyl)phenyl]-1,2,4-thiadiazol-5-ylmethanol; 3-(4-Trifluoromethylphenyl)-1,2,4-thiadiazole-5-methanol; 1,2,4-Thiadiazole-5-methanol, 3-[4-(trifluoromethyl)phenyl]-; (3-(4-(Trifluoromethyl)phenyl)-1,2,4-thiadiazol-5-yl)methanol
EINECS	Contact for details

Quality Control

Our (3-[4-(Trifluoromethyl)Phenyl]-1,2,4-Thiadiazol-5-Yl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.