Description

n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3,5-Dimethoxybenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant value in the research and development of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily sought after by pharmaceutical R&D laboratories, biotechnology companies, and fine chemical manufacturers engaged in the synthesis of complex active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates, particularly kinase inhibitors.
• Oncology Research: Used in the development of targeted cancer therapies due to its specific molecular scaffold.
• Medicinal Chemistry: Serves as a core structure for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Research: Potential use as a reference standard or probe in biochemical assays and enzyme inhibition studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Utilized in university and institutional labs for cutting-edge pharmaceutical and chemical research.

Basic Information

Product Name	n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3,5-Dimethoxybenzamide
CAS No.	848673-21-2
Molecular Formula	C27H25N5O5
Molecular Weight	499.52 g/mol
Synonyms	3,5-Dimethoxy-N-[3-cyano-1-(3-methoxypropyl)-10-methyl-5-oxo-1,5-dihydro-2H-dipyrido[1,2-a:2',3'-d]pyrimidin-2-ylidene]benzamide; BMS-777607 Intermediate; Cabozantinib-related intermediate; XL184 Intermediate; 848673-21-2; UNII-9K9N8U508I; 2H-Dipyrido[1,2-a:2',3'-d]pyrimidine-2-carboxamide derivative
EINECS	Contact for details

Quality Control

Our n-[3-Cyano-1-(3-Methoxypropyl)-10-Methyl-5-Oxo-1,5-Dihydro-2H-Dipyrido[1,2-A:2,3-D]Pyrimidin-2-Ylidene]-3,5-Dimethoxybenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at -20°C. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to light brown solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.