Description

2-Bromo-1,3-Difluoro-4-Methylbenzene is a high-purity halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the construction of complex molecular architectures. This compound is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for developing new active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, where the bromo and fluoro substituents enhance biological activity.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for electronic and display materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Ligand & Catalyst Development: Employed in the creation of specialized ligands and organocatalysts for asymmetric synthesis.
• Polymer Modification: Used to introduce fluorine and bromine functional groups into polymer backbones to alter thermal stability and chemical resistance.

Basic Information

Product Name	2-Bromo-1,3-Difluoro-4-Methylbenzene
CAS No.	847502-89-0
Molecular Formula	C7H5BrF2
Molecular Weight	207.02 g/mol
Synonyms	1-Bromo-2,4-Difluoro-5-Methylbenzene; 2,4-Difluoro-5-Methylbromobenzene; 5-Bromo-2,4-Difluorotoluene; 2-Bromo-1,3-difluoro-4-methyl-benzene; Benzene, 2-bromo-1,3-difluoro-4-methyl-; 4-Methyl-2-bromo-1,3-difluorobenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-1,3-Difluoro-4-Methylbenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and lot-to-lot consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.