Description

4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its unique trifluoromethylpyridine-benzaldehyde hybrid structure. This compound is critical for medicinal chemistry research and development, offering a versatile building block for creating novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D teams and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for synthesizing targeted molecules with enhanced biological activity and metabolic stability.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in oncology, CNS, and anti-inflammatory therapeutic areas.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group can improve efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a starting material for creating specialized ligands in catalytic systems and metal-organic frameworks (MOFs).
• Material Science: Employed in the research of organic electronic materials and functional polymers due to its conjugated system.
• Chemical Biology Probes: Utilized to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde
CAS No.	847446-85-9
Molecular Formula	C13H8F3NO
Molecular Weight	251.21 g/mol
Synonyms	2-[4-Formylphenyl]-3-(trifluoromethyl)pyridine; 4-[3-(Trifluoromethyl)-2-pyridinyl]benzaldehyde; 4-(3-Trifluoromethylpyridin-2-yl)benzaldehyde; 2-(4-Formylphenyl)-3-trifluoromethylpyridine; Benzaldehyde, 4-[3-(trifluoromethyl)-2-pyridinyl]-; 847446-85-9
EINECS	Contact for details

Quality Control

Our 4-(3-(Trifluoromethyl)Pyridin-2-Yl)Benzaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for research and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong bases, and reducing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.