Description

2-Fluoro-6-(Trimethylsilyl)Pyridine is a versatile organosilicon building block that combines a fluorinated pyridine core with a reactive trimethylsilyl group. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily sought after by pharmaceutical, agrochemical, and material science industries for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and stability.
• Ligand Precursor: Serves as a starting material for creating specialized ligands in catalysis and coordination chemistry.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and advanced polymers.
• Cross-Coupling Reactions: The trimethylsilyl group can be utilized in various metal-catalyzed coupling reactions to form new carbon-carbon bonds.
• Fluorine Chemistry Studies: A valuable reagent for investigating structure-activity relationships (SAR) in fluorinated heterocyclic compounds.

Basic Information

Product Name	2-Fluoro-6-(Trimethylsilyl)Pyridine
CAS No.	847226-07-7
Molecular Formula	C8H12FNSi
Molecular Weight	169.27 g/mol
Synonyms	6-Fluoro-2-(trimethylsilyl)pyridine; 2-(Trimethylsilyl)-6-fluoropyridine; Pyridine, 2-fluoro-6-(trimethylsilyl)-; 2-Fluoro-6-trimethylsilylpyridine; TMS-2-Fluoropyridine; 6-Fluoro-2-pyridyltrimethylsilane
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Trimethylsilyl)Pyridine is produced and tested under strict quality management protocols to ensure high purity and batch-to-batch consistency. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.