Description

2-Cyano-4-Fluoropyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. This compound is prized for its unique reactivity, where the cyano and fluoro substituents on the pyridine ring enable precise molecular modifications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients. Our supply ensures consistent quality and reliable availability for your most demanding synthetic pathways.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and CNS drug research.
• Agrochemical Synthesis: Building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and metabolic stability.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Precursor: Intermediate in the synthesis of functionalized polymers, liquid crystals, and electronic materials.
• Chemical Biology Probes: Serves as a core structure for designing molecular probes and tags used in biochemical assays and diagnostic research.
• Custom Synthesis and Contract Manufacturing: Supplied to CROs and CDMOs for client-directed research and scale-up projects.

Basic Information

Product Name	2-Cyano-4-Fluoropyridine
CAS No.	847225-56-3
Molecular Formula	C6H3FN2
Molecular Weight	122.10 g/mol
Synonyms	4-Fluoro-2-cyanopyridine; 2-Pyridinecarbonitrile, 4-fluoro-; 4-Fluoropyridine-2-carbonitrile; 4-Fluoro-2-pyridinecarbonitrile; 2-Cyano-4-fluoropyridine; 847225-56-3; 4-Fluoro-2-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-4-Fluoropyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the product meets the high-purity standards required for research and scale-up. Our quality control includes identity confirmation by spectroscopic methods (NMR, IR), purity assessment by HPLC/GC, and control of key impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.