Description

Ro4917838 (R Enantiomer) is a high-purity, single-enantiomer chemical compound used as a critical intermediate or reference standard in advanced pharmaceutical research and development. This compound matters for its role in enabling the synthesis and study of stereospecific drug candidates, where the biological activity is highly dependent on the correct three-dimensional configuration. It is primarily needed by pharmaceutical companies, contract research organizations (CROs), and academic institutions engaged in medicinal chemistry, process development, and analytical method validation for new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of novel active pharmaceutical ingredients (APIs) targeting specific biological pathways.
• Reference Standard: Used for analytical method development, validation, and quality control (QC) testing in HPLC, LC-MS, and chiral separation techniques.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies to investigate the potency and selectivity of drug candidates.
• Process Chemistry Development: Serves as a starting material or intermediate for optimizing scalable and cost-effective synthetic routes under GMP conditions.
• Biochemical Assay Development: Utilized as a ligand or inhibitor in high-throughput screening (HTS) and in vitro pharmacological profiling.
• Academic Research: Supports fundamental studies in organic synthesis, asymmetric catalysis, and stereochemistry at universities and research institutes.

Basic Information

Product Name	Ro4917838 (R Enantiomer)
CAS No.	845614-12-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ro 4917838; (R)-Ro4917838; Ro-4917838 R enantiomer; 845614-12-2; UNII-Contact for details; (R)-enantiomer of Ro4917838; Ro4917838 (R)-Form
EINECS	Contact for details

Quality Control

Our Ro4917838 (R Enantiomer) is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical characterization, including chiral purity assessment by HPLC, to meet the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) providing identity, purity, and impurity profile is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is strictly light-sensitive (protect from all light exposure) and hygroscopic (moisture-sensitive). For long-term storage, consider storing under an inert atmosphere in a desiccated environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.