Description

Quinoxaline-5-Sulfonylchloride CAS NO 844646-88-4 is a high-purity sulfonyl chloride derivative of the quinoxaline heterocycle, serving as a critical building block in advanced organic synthesis. Its primary value lies in its reactivity as a sulfonylation reagent, enabling the efficient introduction of the quinoxaline-5-sulfonyl moiety into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, especially in kinase inhibitor and antiviral research.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides with specific modes of action.
• Material Science: Precursor for functional polymers, dyes, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling proteins or modifying biomolecules in probe development.
• Organic Synthesis Research: Versatile reagent for constructing complex heterocyclic systems and sulfonamide libraries in medicinal chemistry.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of client-specific advanced intermediates.

Basic Information

Product Name	Quinoxaline-5-Sulfonylchloride
CAS No.	844646-88-4
Molecular Formula	C8H5ClN2O2S
Molecular Weight	228.65 g/mol
Synonyms	5-Quinoxalinesulfonyl chloride; Quinoxaline-5-sulfonyl chloride; 844646-88-4; Quinoxalin-5-ylsulfonyl chloride; 5-(Chlorosulfonyl)quinoxaline; Quinoxaline-5-SO2Cl; Quinoxaline sulfonyl chloride derivative; 5-Quinoxalinesulphonyl chloride
EINECS	Contact for details

Quality Control

Our Quinoxaline-5-Sulfonylchloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, ensuring compliance with your research and production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.