Description

A 769662 is a potent and selective small molecule activator of AMP-activated protein kinase (AMPK). This compound is a critical research tool for studying cellular energy homeostasis, metabolic regulation, and related signaling pathways. It is primarily utilized by researchers and scientists in the fields of biochemistry, pharmacology, and metabolic disease research. The product, with CAS No. 844499-71-4, is supplied as a high-purity reference standard to ensure reliable and reproducible experimental results.

Application

• Biochemical Research: Used as a specific AMPK activator to investigate the enzyme's role in cellular energy sensing and metabolic control.
• Pharmacological Studies: Employed in vitro and in vivo to explore potential therapeutic applications for metabolic disorders such as type 2 diabetes and obesity.
• Signal Transduction Analysis: A key tool for dissecting the AMPK signaling pathway and its interactions with other metabolic regulators.
• Cell Biology: Used to study the effects of AMPK activation on processes like autophagy, cell growth, and mitochondrial function.
• Drug Discovery: Serves as a reference compound and a starting point for the development of novel AMPK-targeting therapeutics.
• Academic & Industrial R&D: Essential for basic research and pre-clinical development in pharmaceutical and biotechnology companies.

Basic Information

Product Name	A 769662
CAS No.	844499-71-4
Molecular Formula	C24H20N4O2S
Molecular Weight	428.51 g/mol
Synonyms	AMPK Activator A-769662; A-769662; 4-Hydroxy-3-(2'-hydroxybiphenyl-3-yl)-6-oxo-6,7-dihydrothieno[3,2-b]pyridine-5-carbonitrile; Thienopyridone A-769662; AMPK agonist A 769662; 6,7-Dihydro-4-hydroxy-3-(2'-hydroxy[1,1'-biphenyl]-3-yl)-6-oxothieno[2,3-b]pyridine-5-carbonitrile
EINECS	Contact for details

Quality Control

Our A 769662 is manufactured under strict quality control protocols to ensure high chemical purity and batch-to-batch consistency, suitable for sensitive research applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for research chemicals to guarantee product integrity and reliable performance in your experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥98.0%
Water Content	≤0.5%
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.