Description

1-Bromo-4-Fluoro-2-(Methoxymethyl) Benzene is a high-purity, multi-functional halogenated aromatic building block essential for advanced organic synthesis. This compound matters because it provides a versatile scaffold for constructing complex molecules, offering distinct reactivity at the bromo, fluoro, and methoxymethyl sites for selective functionalization. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for creating novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a substituted benzene core with halogen handles for cross-coupling reactions.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atom can enhance biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the creation of novel organic electronic materials, such as liquid crystals or charge-transport molecules, due to its aromatic structure and substituents.
• Custom Chemical Synthesis: A valuable building block for contract research and manufacturing organizations (CROs/CMOs) producing bespoke compounds for client projects.
• Academic Research: Utilized in university and institutional labs for methodological studies in cross-coupling, fluorination chemistry, and heterocycle formation.

Basic Information

Product Name	1-Bromo-4-Fluoro-2-(Methoxymethyl) Benzene
CAS No.	842167-67-3
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-Bromo-5-Fluorobenzyl Methyl Ether; 4-Fluoro-2-(Methoxymethyl)-1-Bromobenzene; 1-Bromo-4-Fluoro-2-(Methoxymethyl)benzene; 2-(Methoxymethyl)-1-bromo-4-fluorobenzene; Benzene, 1-bromo-4-fluoro-2-(methoxymethyl)-; 5-Fluoro-2-(methoxymethyl)bromobenzene; (2-Bromo-5-fluorophenyl)methanol methyl ether
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Fluoro-2-(Methoxymethyl) Benzene is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment ensures material consistency and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider using an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.