Description

2-Fluoro-6-(Thiophen-2-Yl)Pyridine is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in its unique molecular architecture, which combines a pyridine ring with a thiophene moiety and a strategically placed fluorine atom, enabling precise modifications to the electronic and steric properties of target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) active compound libraries.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioavailability and metabolic stability.
• Material Science Precursor: Serves as a building block for organic semiconductors, liquid crystals, and metal-organic frameworks (MOFs) due to its conjugated system.
• Ligand Synthesis: Employed in the preparation of specialized ligands for catalysis and coordination chemistry.
• Chemical Biology Probes: Useful for creating fluorescent tags or molecular probes to study biological processes.
• Cross-Coupling Reactions: Acts as a versatile substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct complex biaryl systems.

Basic Information

Product Name	2-Fluoro-6-(Thiophen-2-Yl)Pyridine
CAS No.	842136-47-4
Molecular Formula	C9H6FNS
Molecular Weight	179.21 g/mol
Synonyms	2-(2-Fluoropyridin-6-yl)thiophene; 6-(Thiophen-2-yl)-2-fluoropyridine; 2-Fluoro-6-(2-thienyl)pyridine; 2-Fluoro-6-thiophen-2-ylpyridine; 2-Fluoro-6-(thiophen-2-yl)pyridine; 2-Fluor-6-(thiophen-2-yl)pyridin; 842136-47-4
EINECS	Contact for details

Quality Control

Every batch of 2-Fluoro-6-(Thiophen-2-Yl)Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency meet the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.